TOP GUIDELINES OF FENTANYL ARTIST

bosentan will decrease the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. Coadministration of fentanyl with CYP3A4 inducers may lead to a lower in fentanyl plasma concentrations, deficiency of efficacy or, maybe, improvement of a withdrawal syndrome in a very affected individual